Podcast

Dylan Patel — Deep dive on the 3 big bottlenecks to scaling AI compute

Plus, why an H100 is worth more today than 3 years ago

Mar 13 • Dwarkesh Patel

2:30:44

The most important question nobody's asking about AI

“Preface to the highest stakes negotiations in history.”

Mar 11 • Dwarkesh Patel

24:38

Why Leonardo was a saboteur, Gutenberg went broke, and Florence was weird – Ada Palmer

Ambassador visiting Renaissance Florence: “Where am I? None of this has existed for a thousand years."

Mar 6 • Dwarkesh Patel

2:02:19

Dario Amodei — "We are near the end of the exponential"

"That's why I'm sending this message of urgency"

Feb 13 • Dwarkesh Patel

2:22:19

Elon Musk — "In 36 months, the cheapest place to put AI will be space”

“Those who live in software land are about to have a hard lesson in hardware.”

Feb 5 • Dwarkesh Patel

2:49:45

Adam Marblestone — AI is missing something fundamental about the brain

The brain's secret sauce is its reward functions, not its architecture.

Dec 30, 2025 • Dwarkesh Patel

1:49:53

Sarah Paine — Why Russia Lost the Cold War

Oil crisis, Sino-Soviet split, ethnic rebellions, and arms build-up

Dec 19, 2025 • Dwarkesh Patel

1:54:54

Ilya Sutskever — We're moving from the age of scaling to the age of research

“These models somehow just generalize dramatically worse than people. It's a very fundamental thing.”

Nov 25, 2025 • Dwarkesh Patel

1:36:03

Satya Nadella — How Microsoft is preparing for AGI

Plus a tour of Fairwater 2, the most powerful AI datacenter in the world

Nov 12, 2025 • Dwarkesh Patel

1:27:47

Sarah Paine — How Russia sabotaged China's rise

Plus, where Russia and China go from here

Oct 31, 2025 • Dwarkesh Patel

1:30:36

Andrej Karpathy — AGI is still a decade away

"The problems are tractable, but they're still difficult”

Oct 17, 2025 • Dwarkesh Patel

2:25:19

Nick Lane – Life as we know it is chemically inevitable

Life is continuous with Earth’s geochemistry

Oct 10, 2025 • Dwarkesh Patel

1:20:08

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